Brad Porter will take over the CEO role from Ian McCrae in late August.
McCrae will continue to play a key part in the company as an executive director with a particular focus on products.
He has decided the time is right to step back to focus on his health and set in motion this next phase of the business after 30 years as CEO.
Brad Porter is currently Fisher - Paykel Healthcare international sales commercial general manager, where he helped to lead the 1,300-person global sales team across 53 countries.
McCrae says Orion Health has found a leader with the vitality, passion and experience needed to achieve the company's significant global growth goals.
"Orion Health isn't a typical global healthcare company. We're better described as a pack of startups, doing everything we can to solve the most pressing problems in healthcare with groundbreaking new technology," McCrae says.
"Orion Health has always been a proud family business, a sense of whānau is at the heart of our company values.
"As my son-in-law, we have grown to understand each other, and Brad knows what makes Orion Health tick, and he has helped me to develop our strategy for the future.
"Brad is an inspiring leader. He brings a wealth of experience in global sales while closely aligning top local research and development. A perfect match for what we do at Orion Health."
Porter says the first jobs on his list will be visiting Orion Health's global network of offices and getting a clear understanding of the intricacies of the business.
"No one understands the specialised needs of digital health like Orion Health, it's the global leader in population health technology and health data science," Porter says.
"Orion Health has the world's number one digital health platform and is innovating game-changing new technology like the Digital Front Door, which puts people at the heart of healthcare.
"I can't wait to join the immensely talented team and lead the next revolution of healthcare."